Neuropathy & Nerve Pain

Peripheral neuropathy refers to damage or dysfunction in the peripheral nerves, the network that transmits signals between the central nervous system and the rest of the body. It produces symptoms including numbness, tingling, burning pain, weakness, and balance difficulties, most commonly in the hands and feet. The causes are numerous: diabetic neuropathy, chemotherapy-induced neuropathy, autoimmune neuropathy, nutritional deficiency neuropathies, and idiopathic forms all require different investigative and therapeutic approaches.

Nutritional status is critically important in nerve health. B12 deficiency, common in individuals on metformin, proton pump inhibitors, or plant-based diets without supplementation, is a leading cause of peripheral neuropathy that is completely addressable. B1 (thiamine), B6, alpha-lipoic acid, and acetyl-L-carnitine all play roles in nerve function and protection, and deficiencies or insufficiencies in these nutrients impair the nerve's ability to maintain myelin integrity and conduct signals properly.

Blood sugar control is essential in diabetic neuropathy, reducing glycemic variability reduces the ongoing nerve damage while targeted supplementation with alpha-lipoic acid has demonstrated the ability to reduce neuropathic pain scores in clinical trials. For other forms of neuropathy, reducing inflammation, supporting detoxification, and addressing the underlying immune or vascular component are central therapeutic strategies. Holistic practitioners work to identify the specific drivers of neuropathy in each individual and apply targeted interventions that support nerve health from multiple angles.